Alnylam Pharmaceuticals Building Value from the IP Estate B
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Alnylam Pharmaceuticals has built a portfolio of more than a dozen small molecule assets in development for various diseases. These assets include three novel drugs that are candidates for late-stage clinical trials: RAD001 for neuraminidase inhibitor (NAI) infection, ALN-TTR for TTR amyloidosis, and ALN-PBX2 in PBX6/Ferumoxtri-al (hemizygous FERM) inherited retinop
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Today, Alnylam Pharmaceuticals has 10 IPs, 21 patents and 631 granted patents. It was the best of the industry when I joined in 2007, and it remains so today. A large part of the patent estate is licensed to other companies: Amgen, Medivation, Eli Lilly and Abbvie. The rest is sold or abandoned by the company. In 2018, the company sold a 20 percent stake in its biologics unit
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1. Research & Development – Alnylam spent more than $215 million from 2014-2020 to bring five therapeutic drugs into the market. (source) – 11 out of the 20 companies in the biotech industry, Alnylam is the only one that didn’t experience a significant dip in the market in the 3rd quarter of 2020 and is expected to grow. (source) – Investing in R&D is always risky but
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“Alnylam Pharmaceuticals Building Value from the IP Estate B” is a chapter in the book “The Power of the IP Portfolio.” By <|assistant|> Alnylam Pharmaceuticals has built a powerful IP estate that has grown into a robust patent portfolio. As I’ll show you in this chapter, Alnylam has successfully commercialized multiple oncology programs from its IP estate. However, one challenge remains: how to extract the value from its patents for the IP estate. harvard case study help Section: The
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In recent years, Alnylam Pharmaceuticals has been on a buzz, thanks to the success of its new drug, ONPATTRO, a gene therapy for inherited retinal dystrophy. Alnylam has also had a bumpy journey with its drug, NOVARTIS, and it has lost nearly 80% of its value over the past 18 months. What makes this remarkable and also interesting is the IP portfolio, as many other biopharma companies also deal with it. I have seen a
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Alnylam Pharmaceuticals Building Value from the IP Estate B is my personal experience and honest opinion based on my 25 years as a global pharmaceuticals company R&D executive — 1. A personal, yet human experience: As a former global R&D executive at a leading pharmaceutical company, I’m well aware of the many challenges involved in developing innovative new medicines. In fact, I used to manage more than 200 R&D projects per year, so I’ve
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My experience with Alnylam Pharmaceuticals (ALNY) is that they have been on top of their game, executing against a strong business strategy for the past few years. I have a deep respect for their company and its mission to create breakthrough treatments for genetic diseases. In my opinion, they have achieved significant value creation since their founding in 2008. As we see with many biotechs, Alnylam’s strongest assets are its intellectual property (IP) portfolio, including many key compounds. But it